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Pharmaceutical | Freeze-drying and Vacuum Ovens

Posted by Jennifer Collins on May 4, 2020 9:00:00 AM

Pharmaceutical Freeze-drying and Vacuum Drying for Research and Manufacturing in the .01 Torr to 400 Torr Range Vacuum Pressure is used in Pharmaceutical Manufacturing to:  Help create bulk and active ingredients for FDA approved drug products Increase the shelf-life of a drug product Sterilize medical devices  Lyophilization, also known as freeze-drying, is a process used for preserving biological material by removing the water from the sample, which involves first freezing the sample and then drying it, under a vacuum, at very low temperatures. The low pressure environment helps minimize oxidation during drying. Lyophilized samples may be stored much longer than untreated samples. The resulting precipitate is a shelf-stable powder. This powdered drug is later reconstituted at point of care for patient use.
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Topics: Medical/Pharma, Researcher topics, Vacuum Regulation, Vacuum system setup, vacuum system needs, Rough Vacuum, medical, laboratory, vacuum drying, freeze drying, vacuum oven

Medical Vacuum Applications | Vacuum Sterilization

Posted by Jennifer Collins on Apr 9, 2020 12:37:00 PM

Vacuum Instrumentation for Vacuum Drying and Sterilization of Medical Devices Sterilization of medical equipment is vitally important to render a product free from viable microorganisms (such as bacteria, fungi, and viruses).  Steam is used in the many sterilization processes. The steam is put under pressure that is higher than atmospheric pressure (> 1 bar). A sterilizer configured to run a vacuum cycle will be equipped with a vacuum system. A typical vacuum cycle will begin with a series of alternating steam and pressure injections. The use of a vacuum controller to lower the vacuum pressure this will remove air from the chamber.
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Topics: Medical/Pharma, Researcher topics, Vacuum Regulation, Vacuum system setup, vacuum system needs, Rough Vacuum, medical, laboratory

Vacuum Instruments For Lyophilizers | What You Need To Know

Posted by Eric Beardslee on Jan 7, 2015 12:13:43 PM

Accurate, reliable vacuum readings during freeze drying processes is one of the bigger challenges faced by users of older lyophilizers, and an even greater challenge faced by those designing new systems.
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Topics: Medical/Pharma, Food/Beverage

Industry Spotlight: Medical Application of Aspiration Vacuum Control

Posted by Tim Collins on Oct 21, 2014 8:00:00 AM

A surgical equipment manufacturer asked us to craft a product that would help physicians maintain consistent vacuum control during surgical procedures such as liposuction. Existing vacuum pressure controllers could not maintain consistent pressure, resulting in a build-up of vacuum pressure during a blockage of the cannula, resulting in a stall of vacuum, followed by an increase in vacuum pressure after the blockage was removed. 
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Topics: Medical/Pharma